Growth Hormone 1 anticorps (C-Term)

N° du produit ABIN2776980

L’anticorps Lapin Polyclonal anti-Growth Hormone 1 a été validé pour WB. Il convient pour détecter Growth Hormone 1 dans des échantillons de Humain, Rat, Souris, Porc, Boeuf (Vache), Cheval, Mouton, Chévre et Lapin.

Aperçu rapide pour Growth Hormone 1 anticorps (C-Term) (ABIN2776980)

Antigène: Growth Hormone 1 (GH1)

Reactivité: Humain, Rat, Souris, Porc, Boeuf (Vache), Cheval, Mouton, Chévre, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Growth Hormone 1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Growth Hormone 1 anticorps

Épitope: C-Term

Séquence: TYSKFDTNSH NDDALLKNYG LLYCFRKDMD KVETFLRIVQ CRSVEGSCGF

Homologie: Cow: 100%, Goat: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against GH1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 177 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Growth Hormone 1

Antigène: Growth Hormone 1 (GH1)

Autre désignation: GH1

Sujet: The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation, an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.
Alias Symbols: GH, GH-N, GHN, IGHD1B, hGH-N
Protein Interaction Partner: GHR, BAG3, BTRC, PRLR, GH1, SHC1, STRAP, LTA4H,
Protein Size: 177

Poids moléculaire: 20 kDa

ID gène: 2688

NCBI Accession: NM_022560, NP_072054

UniProt: A6NEF6

Pathways: Signalisation NF-kappaB, Signalistation JAK/STAT, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process